Physicians should take certain precautions in prescribing the first-generation antihistamine hydroxyzine to minimize the drug’s risk for potentially fatal heart arrhythmias, the European Medicines Agency (EMA) announced recently.
Long-acting opioids were associated with a greater than 2-fold risk for unintentional overdose compared with short-acting formulations, according to a cohort study published online February 16 in JAMA Internal Medicine. Moreover, the risk was more than 5-fold greater in the first 2 weeks of using a long-acting opioid.
A committee of the European Medicines Agency (EMA) has just a few days ago recommended suspending the sale of roughly four dozen generic drugs that are used for conditions including diabetes, depression, and hypertension because they noted that their approvals were based on flawed clinical studies conducted only in India. The US Food and Drug Administration (FDA) has not yet taken action on the issue. But they are in the process of reviewing this issue now.
Statins are one of the most popular drugs. They reduce serum lipids implicated in producing cardiac and vascular disease. Statins have side effects and are well-known, such as liver disease and muscle pain. Now a new side effect has been discovered.
As Emergency Departments swell while suffering the repercussions of the Affordable Healthcare Act, our nation's youth increase their use of mind-altering drugs, in particular, Ecstasy (Mollys).
Over the past few years advancements have been made in the approach to, and management of, elevated blood glucose. In the emergency room, elevated blood glucose (hyperglycemia) is commonly encountered. Often times, patients who present with unrelated problems are coincidentally found to have elevated blood glucose. Many emergency physicians dismiss this finding as a chronic finding and therefore, do not investigate further. But this is a mistake that often results in an adverse patient outcome, and later a medical-legal inquiry and possibly a medical malpractice lawsuit.
Elevated blood glucose can be a tip-off that there are serious metabolic abnormalites present. A detailed investigation is warranted in the ER because many of these patients are asymptomatic and will not seek follow-up medical care until they become symptomatic, by which time their condition may be far advanced. The following review article on the approach to hyperglycemia in the ER is current and represents the standard of care approach to these patients.
Ambien is the most common sleeping medication at the present time. Unfortunately, although Ambien is usually quite effective at facilitating sleep, it also has been found to have several disturbing side effects, including tolerance, addiction, and somambulism. Recently the FDA has revised its dosing guidelines on how the medication should be used. The news brief follows:
Ambien (zolpidem) is currently the most commonly used sleeping medication on the market. Most physicians believe, unknowingly, that it can be prescribed with impunity. This is not the case. Ambien has many side effects that have resulted in a big increase in visits to emergency departments.
The FDA finally approved a new drug which ameliorates the severe constipation that accompanies the use of Opiates. Constipation is one of the main side effects that causes individuals to stop Opiate medication prematurely without any other option for their pain. This addition to treatment with opiates is a notable advancement.
